REAL-TIME AND LABEL FREE ANALYZER FOR IN -VITRO AND IN -VIVO DETECTION OF CANCER

ABSTRACT

A method for in-vivo cancer diagnosis within a living tissue. The method includes preparing an electrochemical probe by fabricating three integrated electrodes via coating a layer of vertically aligned multi -walled carbon nanotubes (VAMW CNTs) on tips ofthree electrically conductive biocompatible needles , putting the tips of the three integrated electrodes in contact with a portion of the living tissue by inserting the tips of the three integrated electrodes into the portion of the living tissue , recording an electrochemical response from the portion of the living tissue , where the electrochemical response may include a cyclic voltammetry (CV) diagram with an oxidation current peak corresponding to a hypoxic glycolysis chemical reaction in biological cells within the portion of the living tissue , and detecting a cancer- involving status of the portion of the living tissue based on the oxidation current peak.